Graph Mining

Mining the Genome for Epigenetic Properties

Contact Student: Md Haque, mhaque@eecs.wsu.edu

 

Description: The objective is to use to Data mining techniques on Microarray data (Epigenetic) to identify genome wide Methylation changes. These changes are based on the effects of early developmental exposures to environmental compounds on epigenetic features and the potential for its transgenerational transmission.

Dataset: Microarray data based on Rattus norvegicus, Mus musculus

   http://skinner.wsu.edu/microarray.html

Relevant Publications:

Epigenetic Transgenerational Actions of Vinclozolin on Promoter Regions of the Sperm Epigenome Guerrero-Bosagna C, Settles M, Lucker B, Skinner MK, 2010 Epigenetic Transgenerational  Actions of Vinclozolin on Promoter Regions of the Sperm Epigenome. PLoS ONE 5(9): e13100. doi:10.1371/journal.pone.0013100